Themes

Session I: Biological Targets and Radiation Therapy
Session II: Targeting the Microenvironment:
Hypoxia and Angiogenesis
Session III: Target Imaging: Imaging Biology for Target Discovery
Session IV: Shifting Targets, Changing Volumes: Adaptive Image Guidance
Session V: Radiation Therapy in 2010: What does the future hold?
A clinically oriented view into the future of radiation therapy for cervix cancer and breast cancer.
What does the future hold? How do we define and measure success?
   

Program

Friday, May 5, 2006

7:30-8:15 Registration and Breakfast
8:15-8:30 Welcome and Opening Remarks
Mary Gospodarowicz, Professor and Chair,
Department of Radiation Oncology, University of Toronto
8:30-12:00 Session I: Biological Targets in Radiation Therapy
 Moderator: Robert Bristow
8:30-9:15 Keynote Presentation
Real Time Imaging of Signal Transduction In Vivo
David Piwnica-Worms
9:15-9:30 DNA-dsb Repair as a Target for Radiotherapy
Robert Bristow
9:30-9:45 Cancer to Cosmetics - HTS for Drug Discovery in Head & Neck Cancer
Fei-Fei Liu
9:45-10:00 Targeting the EGFR to Improve the Radiation Therapeutic Ratio
Katherine Vallis
10:00:10:15 Combining New Molecularly Targeted Agents with Radiotherapy in Phase I Trials
Lillian Siu
10:15-10:45 Break
10:45-11:15 Keynote Presentation
Identification of Molecularly Targeted Radiosensitizers
Philip Tofilon
11:15-12:00 Panel Discussion
Moderators: Robert Bristow and David Piwnica-Worms
12:00-1:30 Lunch
1:30-4:45 Session II: Targeting the Microenvironment: Hypoxia, Angiogenesis and More
Moderators: Michael Milosevic and Anthony Fyles
1:30-2:30 Targeting Hypoxia, IFP and Angiogenesis
Michael Milosevic and Anthony Fyles
2:00-3:00 Targeting the Microenvironment to Avoid Normal Tissue Toxicity
Shun Wong
3:00-3:30 Break
3:30-4:00 Panel Discussion
Clinical Implications and Areas for Further Research
Moderators: Richard Hill and Michael Milosevic
4:00-4:45 Keynote Presentation
Challenges in the Era of Image-Guided Therapy
Clifford Chao
4:45-6:00 Wine and Cheese Reception with Poster Walkabout

Saturday, May 6, 2006
7:45–8:30 Registration and Breakfast
8:30–8:45 Opening Remarks
David Jaffray
8:45–12:00 Session III: Imaging Biology for Target Discovery
Moderators: David Jaffray and Yee Ung
8:45–9:30 Keynote Presentation
Biologically Conformal Radiation Therapy: Validation of Image-Defined Target Volumes
Pat Zanzonico
9:30–9:45 Imaging Lymph Nodes
Robert Dinniwell
9:45-10:00 Imaging Cell Death
Gregory Czarnota
10:00–10:15 Imaging Hypoxia (Functional CT)
Ivan Yeung
10:15–10:30 Break
10:30–11:00 Spatio-Temporal Targeting and Amplification of Radiation Response (STTARR)
David Jaffray
11:00–11:15 Quantifying Tumour and Normal Tissue Response through Deformable Modeling
Kristy Brock
11:15–12:00 Panel Discussion
Moderators: David Jaffray and Yee Ung
12:00–1:30 Lunch
1:30–3:00 Session IV: Shifting Targets, Changing Volumes: Adaptive Image Guidance
Moderators: Laura Dawson and Peter O’Brien
1:30–2:15 Keynote Presentation
Image-guided Radiation Therapy: How will the system respond to new information?
David Jaffray
2:15–2:30 Adaptive Planning and Delivery to Account for Anatomical Changes Induced by Radiation Therapy
Michael Sharpe
2:30–2:45 Targeting with PET/CT: Changes and Challenges
Kathy Mah
2:45–3:00 MRI Simulation
Cynthia Menard
3:00–3:30 Break
3:30–4:30 Session V: Wrap-Up
A Clinical Perspective: Radiation Therapy in 2010:
A view into the future of radiation therapy for cervix cancer and breast cancer.
What does the future hold? How do we define and measure success?
Moderators: Jean-Philippe Pignol and Michael Milosevic
4:30 Close and Evaluation
Sponsored by
the University of Toronto
Department of Radiation Oncology